SCHEMBL6546140

SCHEMBL6546140

CCc1ccc(CCCc2ccc(C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2A6 P11509 1/20 0.52
IGF1R P08069 1/20 0.50
ALOX15 P16050 1/20 0.50
KCNH2 Q12809 3/20 0.47
HRH1 P35367 1/20 0.46
IDO1 P14902 1/20 0.44
CHKA P35790 1/20 0.43
HRH3 Q9Y5N1 1/20 0.42
TP53 P04637 2/20 0.42
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
DRD3 P35462 1/20 0.41
ESR1 P03372 2/20 0.40
ADRA2A P08913 2/20 0.40
ADORA3 P0DMS8 2/20 0.40
TACR2 P21452 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546215 0.90 TAAR1 (0.56) TAAR1CYP1A2CYP2A6IGF1RALOX15
SCHEMBL6546878 0.89 CYP1A2 (0.62) TAAR1CYP1A2CYP2A6IGF1RALOX15
SCHEMBL40574 0.87
P-Xylene SCHEMBL28187926 0.87 IDO1 (0.55) TAAR1CYP1A2CYP2A6KCNH2IDO1
SCHEMBL5497395 0.87 IDO1 (0.55) TAAR1CYP1A2CYP2A6KCNH2IDO1
SCHEMBL365821 0.85 CA2 (0.54) TAAR1CYP1A2CYP2A6IGF1RALOX15
SCHEMBL10575050 0.84 TAAR1 (0.62) TAAR1CYP2A6TP53ESR1ADRA2A
Ammonia Solution, Strong SCHEMBL8712487 0.84 IDO1 (0.52) TAAR1CYP1A2CYP2A6KCNH2IDO1
SCHEMBL6546754 0.84 IGF1R (0.64) TAAR1CYP1A2CYP2A6IGF1RALOX15
Water SCHEMBL28807786 0.84 IDO1 (0.52) TAAR1CYP1A2CYP2A6KCNH2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed