SCHEMBL6546352

SCHEMBL6546352

CCc1ccccc1-c1cccc(C(C)C)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.37
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
CSNK2A3 Q8NEV1 1/20 0.37
GABRA1 P14867 5/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
GABRB2 P47870 4/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
FAAH O00519 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30932846 0.85 CA1 (0.43) DPP4NR1H2NR1H3CSNK2A2CSNK2B
SCHEMBL23845156 0.85 GABRA1 (0.45) GABRA1GABRG2GABRB3GABRB2CA1
SCHEMBL8409222 0.81 GABRA1 (0.53) DPP4GABRA1GABRG2GABRB3GABRB2
SCHEMBL8680514 0.81 GABRA1 (0.44) DPP4NR1H2NR1H3GABRA1GABRG2
SCHEMBL8537937 0.77 P2RX7 (0.45) CSNK2A2CSNK2BCSNK2A1CSNK2A3GABRA1
SCHEMBL9621059 0.77 GABRA1 (0.44) GABRA1GABRG2GABRB3GABRB2CA1
SCHEMBL545484 0.76 GABRA1 (0.46) GABRA1GABRG2GABRB3GABRB2CA1
SCHEMBL11654644 0.76 GABRA1 (0.46) GABRA1GABRG2GABRB3GABRB2CA1
SCHEMBL29657207 0.76 GABRA1 (0.46) GABRA1GABRG2GABRB3GABRB2CA1
SCHEMBL198461 0.76 CSNK2A2 (0.52) DPP4CSNK2A2CSNK2BCSNK2A1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed