Phosphoric Acid

Phosphoric Acid

SCHEMBL6546747

CC(=O)C(O)CO.O=P(O)(O)O

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.43
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
GABRR1 P24046 1/20 0.30
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13113139 0.89
SCHEMBL13113138 0.89
SCHEMBL1926067 0.89
Glycerin SCHEMBL15647060 0.77 LMNA (0.45) OR51E2TDP1GABRR1GABBR2GABBR1
Phosphoric Acid SCHEMBL23524667 0.77 OR51E2 (0.37) OR51E2
Phosphoric Acid SCHEMBL1462678 0.76 OR51E2 (0.78) OR51E2PGK1PGK2
Phosphoric Acid SCHEMBL27765779 0.76 OR51E2 (0.78) OR51E2PGK1PGK2
Phosphoric Acid SCHEMBL42321 0.76 OR51E2 (0.78) OR51E2PGK1PGK2
Methacrylic Acid SCHEMBL9511444 0.75 OR51E2 (0.46) OR51E2TDP1
Phosphoric Acid SCHEMBL30182555 0.75 PDE4A (0.38) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1289369-A Riboflavin biosynthesis genes from plants and uses thereof NOVARTIS AG (CH) 2001-03-28 CN claimed
EP-1051504-A2 RIBOFLAVIN BIOSYNTHESIS GENES FROM PLANTS AND USES THEREOF Novartis AG (CH) 2000-11-15 EP claimed
WO-1999038986-A2 RIBOFLAVIN BIOSYNTHESIS GENES FROM PLANTS AND USES THEREOF NOVARTIS AG (CH) 1999-08-05 WO claimed
CN-117568433-B Method for improving production of riboflavin by fermenting bacillus subtilis 黑龙江新和成生物科技有限公司 2024-04-16 CN disclosed
CN-117568433-A Method for improving production of riboflavin by fermenting bacillus subtilis 黑龙江新和成生物科技有限公司 2024-02-20 CN disclosed
WO-2004006855-A2 RHODOCOCCUS EQUI MUTANTS AND VACCINES COMPRISING SAME PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) 2004-01-22 WO disclosed
EP-1379549-A2 SEQUENCE OF THE PHOTORHABDUS LUMINESCENS STRAIN TT01 GENOME AND USES INSTITUT PASTEUR (FR) 2004-01-14 EP disclosed
WO-2002094867-A2 SEQUENCE OF THE PHOTORHABDUS LUMINESCENS STRAIN TT01 GENOME AND USES INSTITUT PASTEUR (FR) 2002-11-28 WO disclosed
CN-1289369-A Riboflavin biosynthesis genes from plants and uses thereof NOVARTIS AG (CH) 2001-03-28 CN disclosed
EP-1051504-A2 RIBOFLAVIN BIOSYNTHESIS GENES FROM PLANTS AND USES THEREOF Novartis AG (CH) 2000-11-15 EP disclosed
WO-1999038986-A2 RIBOFLAVIN BIOSYNTHESIS GENES FROM PLANTS AND USES THEREOF NOVARTIS AG (CH) 1999-08-05 WO disclosed