SCHEMBL6546793

SCHEMBL6546793

O=S(=O)(O)c1cccc(CP)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
HSD17B10 Q99714 3/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.43
HTR6 P50406 2/20 0.40
NPC1 O15118 1/20 0.39
TNF P01375 1/20 0.39
RAB9A P51151 1/20 0.39
NOD1 Q9Y239 1/20 0.39
NAPRT Q6XQN6 1/20 0.38
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CASP6 P55212 1/20 0.37
CASR P41180 2/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
LMNA P02545 1/20 0.35
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21726593 0.83 TSHR (0.55) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL10586812 0.82 TSHR (0.53) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL11413912 0.82 TSHR (0.53) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL3922686 0.80 TSHR (0.57) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL22124430 0.80 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL24199108 0.80 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL698195 0.80 TSHR (0.52) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL331655 0.80 TSHR (0.52) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL11230595 0.80 TSHR (0.52) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL6576001 0.80 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6054260-A Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 2000-04-25 US claimed
EP-0893731-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-01-28 EP disclosed
US-6306570-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY 2001-10-23 US disclosed
US-6054260-A Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 2000-04-25 US disclosed
EP-0893731-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1999-01-27 EP disclosed