SCHEMBL698195

SCHEMBL698195

[CH2]Cc1cccc(S(=O)(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.46
MRGPRX4 Q96LA9 1/20 0.43
HTR6 P50406 2/20 0.40
CASR P41180 2/20 0.39
NPC1 O15118 1/20 0.39
TNF P01375 1/20 0.39
RAB9A P51151 1/20 0.39
NOD1 Q9Y239 1/20 0.39
NAPRT Q6XQN6 1/20 0.38
CASP6 P55212 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
LMNA P02545 2/20 0.37
PMP22 Q01453 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649657 0.85 TSHR (0.48) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL21726593 0.83 TSHR (0.55) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL11413912 0.82 TSHR (0.53) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL10586812 0.82 TSHR (0.53) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL24199108 0.80 ALDH1A1 (0.52) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL2542290 0.80 ALDH1A1 (0.46) ALDH1A1HSD17B10SMN1; SMN2HTR6NPC1
SCHEMBL331655 0.80 TSHR (0.52) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL22124430 0.80 ALDH1A1 (0.52) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL6546793 0.80 ALDH1A1 (0.52) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL7179836 0.80 CA2 (0.61) ALDH1A1HTR6MAPTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421613-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF The Procter & Gamble Company (US) 2012-02-29 EP disclosed
WO-2010123866-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2010-10-28 WO disclosed
EP-0304323-B1 Direct positive silver halide light-sensitive colour photographic material KONISHIROKU PHOTO IND (JP) 1995-11-08 EP disclosed
US-5338655-A Using a spectral sensitizing dyes KONICA CORPORATION (JP) 1994-08-16 US disclosed
EP-0533033-A1 Method for manufacturing a silver halide emulsion KONICA CORPORATION (JP) 1993-03-24 EP disclosed
US-5015563-A Comprising silver halide grains formed in the presence of the mercapto or azaindene compound, a coupler and a high-boiling organic solvent (dielectric of <6); antifogging agents KONICA CORPORATION (JP) 1991-05-14 US disclosed
US-4939078-A HIGH DENSITY KONICA CORPORATION (JP) 1990-07-03 US disclosed
US-4925780-A CONTAINING SPECIFIC SENSITIZING DYES AND ANTI-IRRADIATION COMPOUNDS KONICA CORPORATION (JP) 1990-05-15 US disclosed
EP-0308872-A2 Direct positive-type silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1989-03-29 EP disclosed
EP-0304323-A2 Direct positive silver halide light-sensitive colour photographic material KONICA CORPORATION (JP) 1989-02-22 EP disclosed
EP-0144091-B1 SILVER HALIDE PHOTOGRAPHIC EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1988-11-17 EP disclosed
EP-0256781-A2 Silver halide light-sensitive color photographic material suitable for rapid processing KONICA CORPORATION (JP) 1988-02-24 EP disclosed
US-4594317-A Containing sensitizing dye FUJI PHOTO FILM CO., LTD. (JP) 1986-06-10 US disclosed
US-4582786-A SPECTRAL SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1986-04-15 US disclosed
EP-0144091-A2 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1985-06-12 EP disclosed
US-4218447-A CARDIOTONIC AGENTS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-08-19 US disclosed
US-4040840-A MEROCYANINE DYE HAVING ISOXAZOLE NUCLEUS AND PYRAZOLINE-5-ONE NUCLEUSN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed