SCHEMBL6547085

SCHEMBL6547085

O=C(Oc1cc(Cl)c(O)c(Cl)c1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.54
MAPT P10636 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
MEN1 O00255 2/20 0.54
NSD2 O96028 1/20 0.54
PARP10 Q53GL7 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 1/20 0.47
PKM P14618 1/20 0.47
TTR P02766 1/20 0.47
HPGD P15428 1/20 0.46
F2 P00734 1/20 0.45
LMNA P02545 1/20 0.45
RAB9A P51151 1/20 0.45
PRSS1 P07477 1/20 0.45
ACR P10323 1/20 0.45
TMPRSS15 P98073 1/20 0.45
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7074980 0.89 KMT2A (0.47) KMT2AMAPTTDP1MEN1NSD2
SCHEMBL4623843 0.89 KMT2A (0.47) KMT2AMAPTTDP1MEN1NSD2
SCHEMBL4624925 0.83 KMT2A (0.60) KMT2AMAPTTDP1MEN1NSD2
SCHEMBL2755026 0.82 KMT2A (0.68) KMT2AMAPTTDP1MEN1NSD2
SCHEMBL9299759 0.81 NSD2 (0.73) KMT2AMAPTTDP1MEN1NSD2
SCHEMBL5787359 0.81 MAPT (0.58) KMT2AMAPTTDP1MEN1NSD2
SCHEMBL17383940 0.79 KMT2A (0.59) KMT2AMAPTTDP1MEN1NSD2
SCHEMBL705336 0.79 KMT2A (0.59) KMT2AMAPTTDP1MEN1NSD2
SCHEMBL2298714 0.79 KMT2A (0.60) KMT2AMAPTTDP1MEN1NSD2
SCHEMBL7705090 0.79 KMT2A (0.54) KMT2AMAPTTDP1MEN1NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 KMT2A 2985/4885MAPT 4623/4885TDP1 2528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.