Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 7/20 | 0.53 |
| ▸ | DRD3 | P35462 | 4/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753828 | 0.86 | IGF1R (0.63) | MAPTALDH1A1DRD2DRD3ADRA1A | |
| SCHEMBL10756919 | 0.83 | DRD2 (0.52) | MAPTALDH1A1DRD2DRD3ADRA1A | |
| SCHEMBL6930796 | 0.82 | DRD2 (0.59) | MAPTALDH1A1DRD2DRD3ADRA1A | |
| SCHEMBL7537267 | 0.82 | DRD2 (0.62) | MAPTALDH1A1DRD2DRD3ADRA1A | |
| SCHEMBL7542132 | 0.82 | DRD2 (0.62) | MAPTALDH1A1DRD2DRD3ADRA1A | |
| SCHEMBL6069904 | 0.81 | MAPT (0.51) | MAPTALDH1A1DRD2DRD3ADRA1A | |
| SCHEMBL6070007 | 0.81 | MAPT (0.51) | MAPTALDH1A1DRD2DRD3ADRA1A | |
| SCHEMBL6934504 | 0.81 | HTR1A (0.62) | MAPTALDH1A1DRD2DRD3ADRA1A | |
| SCHEMBL8445548 | 0.81 | HTR1A (0.62) | MAPTALDH1A1DRD2DRD3ADRA1A | |
| SCHEMBL9300157 | 0.81 | HTR1A (0.62) | MAPTALDH1A1DRD2DRD3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906100-B1 | USE OF 5-HT 1A? RECEPTOR ANTAGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE | RECORDATI CHEM PHARM (CH) | 2004-01-28 | — | — | EP | disclosed |
| EP-0906100-A1 | USE OF 5-HT 1A? RECEPTOR ANTAGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997031637-A1 | USE OF 5-HT1A RECEPTOR ANTAGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1997-09-04 | — | — | WO | disclosed |