Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548487 | 0.85 | DPP4 (0.49) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL6548899 | 0.83 | SCN9A (0.48) | DPP4ALDH1A1LMNAL3MBTL1HPGD | |
| SCHEMBL6547083 | 0.75 | PLA2G4A (0.49) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL6547714 | 0.74 | PLA2G4B (0.45) | DPP4ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL13467158 | 0.73 | DPP4 (0.55) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL1333578 | 0.72 | LTA4H (0.56) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL833843 | 0.72 | LTA4H (0.56) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8571707 | 0.72 | LTA4H (0.56) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL1756468 | 0.72 | LTA4H (0.56) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL799787 | 0.72 | LTA4H (0.56) | DPP4ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204714-B1 | BI-OR TERTHIENYL SUBSTITUTED PHOTOCHROMIC NAPHTHO 2,1-B]PYRAN COMPOUNDS | ESSILOR INT (FR) | 2004-01-28 | — | — | EP | disclosed |