Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541978 | 0.77 | ALDH1A1 (0.48) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL15484274 | 0.77 | ALDH1A1 (0.48) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3576477 | 0.75 | — | — | |
| SCHEMBL129566 | 0.75 | — | — | |
| SCHEMBL29162182 | 0.75 | CYP4F2 (0.55) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL371475 | 0.75 | PKM (0.52) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL29368990 | 0.73 | PKM (0.50) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL1164946 | 0.73 | CYP4F2 (0.59) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL15301624 | 0.73 | — | — | |
| SCHEMBL128153 | 0.73 | CYP4F2 (0.44) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379541-A1 | LABELED OLIGONUCLEOTIDES, METHODS FOR MAKING SAME, AND COMPOUNDS USEFUL THEREFOR | ISIS Pharmaceuticals, Inc. (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002079216-A1 | LABELED OLIGONUCLEOTIDES, METHODS FOR MAKING SAME, AND COMPOUNDS USEFUL THEREFOR | ISIS PHARMACEUTICALS, INC. (US) | 2002-10-10 | — | — | WO | disclosed |