SCHEMBL6547240

SCHEMBL6547240

C=C(Cc1ccc(C)cc1)c1ccc(CC)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
PLK1 P53350 1/20 0.40
HPGD P15428 2/20 0.39
CTBP2 P56545 1/20 0.37
SRD5A2 P31213 1/20 0.37
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
ANXA2 P07355 1/20 0.36
S100A10 P60903 1/20 0.36
LMNA P02545 1/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546159 1.00 ALDH1A1 (0.44) ALDH1A1NPC1RAB9AL3MBTL1MEN1
SCHEMBL6546763 0.92 NPC1 (0.48) ALDH1A1NPC1RAB9AL3MBTL1KMT2A
SCHEMBL6546328 0.85 TP53 (0.54) ALDH1A1NPC1RAB9AL3MBTL1MEN1
SCHEMBL25107860 0.83 NPC1 (0.42) ALDH1A1NPC1RAB9AL3MBTL1MEN1
SCHEMBL20716178 0.83 KMT2A (0.50) ALDH1A1NPC1RAB9AL3MBTL1MEN1
SCHEMBL6546799 0.82 L3MBTL1 (0.47) NPC1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL28555686 0.82 KMT2A (0.50) ALDH1A1NPC1RAB9AL3MBTL1MEN1
SCHEMBL6546365 0.82 TP53 (0.50) ALDH1A1RAB9ASMN1; SMN2PLK1LPL
SCHEMBL6547505 0.82 ALDH1A1 (0.48) ALDH1A1NPC1RAB9AL3MBTL1MEN1
SCHEMBL19104060 0.81 NPC1 (0.41) ALDH1A1NPC1RAB9AL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed