Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546799 | 0.92 | L3MBTL1 (0.47) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL6546763 | 0.90 | NPC1 (0.48) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL163962 | 0.85 | MAOA (0.50) | KMT2AL3MBTL1MEN1CES2CES1 | |
| SCHEMBL6547240 | 0.82 | ALDH1A1 (0.44) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL6546159 | 0.82 | ALDH1A1 (0.44) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL6546328 | 0.82 | TP53 (0.54) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL14042627 | 0.82 | FNTA (0.53) | L3MBTL1TDP1CES2CES1LMNA | |
| SCHEMBL28910971 | 0.82 | SRD5A2 (0.52) | KMT2AL3MBTL1RAB9AMEN1CES2 | |
| SCHEMBL25107860 | 0.81 | NPC1 (0.42) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL20716178 | 0.81 | KMT2A (0.50) | KMT2AL3MBTL1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-111978216-A | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2020-11-24 | — | — | CN | disclosed |