Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6547060 | 0.82 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPTPMP22 | |
| SCHEMBL447798 | 0.72 | — | — | |
| SCHEMBL27577387 | 0.71 | NAPRT (0.36) | DAONAPRTKDM4EPOLBMAPT | |
| SCHEMBL456256 | 0.71 | DAO (0.32) | DAO | |
| SCHEMBL2789316 | 0.69 | PTGS2 (0.42) | NAPRTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL5756561 | 0.68 | KDM5A (0.33) | DAOKDM4EALDH1A1LMNA | |
| SCHEMBL447367 | 0.68 | MCL1 (0.33) | DAO | |
| SCHEMBL30825759 | 0.68 | EPHX1 (0.38) | DAONAPRTKDM4EMAPT | |
| SCHEMBL25423722 | 0.67 | — | — | |
| SCHEMBL13754484 | 0.67 | DAO (0.30) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021528-B1 | METHODS OF REFOLDING PROTEINS BY USE OF ZWITTERIONIC LOW MOLECULAR WEIGHT AGENTS | INST GENETICS LLC (US) | 2004-01-28 | — | — | EP | claimed |
| US-6593106-B1 | Culturing prokaryotic cells which have been transformed with a DNA encoding a transforming growth factor protein; substituted pyrroles; useful in preparation of bone morphogenetic proteins | GENETICS INSTITUTE LLC | 2003-07-15 | — | — | US | claimed |