SCHEMBL6548877

SCHEMBL6548877

CC(=NOCCCCCOc1c(C)cc(OCC=C(Cl)Cl)cc1Cl)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 14/20 0.45
PPARG P37231 13/20 0.44
LMNA P02545 2/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
MAPT P10636 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548630 0.99 PPARA (0.46) PPARAPPARGLMNAMAPK1HTT
SCHEMBL6549804 0.97 PPARA (0.43) PPARAPPARGLMNAMAPK1HTT
SCHEMBL6548671 0.94 PPARA (0.43) PPARAPPARGLMNAMAPK1HTT
SCHEMBL6549807 0.93 PPARA (0.44) PPARAPPARGLMNAMAPK1HTT
SCHEMBL6549641 0.92 SLC6A4 (0.38) PPARAPPARGNPC1RAB9AKDM4E
SCHEMBL6547280 0.91 SLC6A4 (0.38) PPARAPPARGHTTNPC1RAB9A
SCHEMBL6547987 0.91 PPARA (0.41) PPARAPPARGLMNAMAPK1HTT
SCHEMBL6549805 0.89 SLC6A4 (0.36) PPARAPPARGHTTNPC1RAB9A
SCHEMBL6548862 0.89 PPARA (0.46) PPARAPPARGLMNAMAPK1HTT
SCHEMBL6548516 0.88 PPARA (0.46) PPARAPPARGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 PPARA 2987/4885PPARG 2821/4885LMNA 3205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.