Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694364 | 0.92 | CYP1A2 (0.35) | CYP1A2OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL11616225 | 0.82 | CYP1A2 (0.35) | CYP1A2OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL18555665 | 0.77 | SIGMAR1 (0.37) | OPRM1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL29106487 | 0.74 | TSHR (0.34) | CYP1A2HTR1AADRA1DMEN1KMT2A | |
| SCHEMBL11375665 | 0.74 | DPP4 (0.37) | OPRM1OPRL1OPRK1CHRM2CHRM4 | |
| SCHEMBL28151905 | 0.72 | CHRM2 (0.36) | CYP1A2OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL31367105 | 0.71 | HTR1A (0.43) | CYP1A2OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL6132327 | 0.71 | OPRM1 (0.47) | OPRM1OPRL1OPRK1OPRD1TSHR | |
| SCHEMBL23532470 | 0.71 | CHRNA1 (0.35) | TSHRCHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL1664714 | 0.70 | TSHR (0.47) | CYP1A2OPRM1OPRL1OPRK1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834525-B1 | Ortho esters as bisphenol A scavenger in polycarbonate product | GEN ELECTRIC (US) | 2004-12-01 | — | — | EP | claimed |
| US-5807912-A | PURIFICATION; HEATING | GENERAL ELECTRIC COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| EP-0834525-A2 | Ortho esters as bisphenol A scavenger in polycarbonate product | GENERAL ELECTRIC COMPANY (US) | 1998-04-08 | — | — | EP | claimed |
| EP-0834525-B1 | Ortho esters as bisphenol A scavenger in polycarbonate product | GEN ELECTRIC (US) | 2004-12-01 | — | — | EP | disclosed |
| US-5807912-A | PURIFICATION; HEATING | GENERAL ELECTRIC COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0834525-A2 | Ortho esters as bisphenol A scavenger in polycarbonate product | GENERAL ELECTRIC COMPANY (US) | 1998-04-08 | — | — | EP | disclosed |