SCHEMBL6547342

SCHEMBL6547342

CC(=NOC(C)(C)C)c1ccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.37
FURIN P09958 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.31
PPARA Q07869 4/20 0.31
PPARD Q03181 2/20 0.31
GAA P10253 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549365 0.98 HTT (0.37) HTTFURINL3MBTL1PPARAPPARD
SCHEMBL6547708 0.89 PRSS1 (0.34) HTTPPARAPPARD
SCHEMBL6547872 0.89 F2 (0.33) HTTPPARAPPARDPPARG
SCHEMBL6547829 0.89 HTT (0.39) HTTFURINL3MBTL1PPARAPPARD
SCHEMBL6548442 0.89 HTT (0.39) HTTFURINL3MBTL1PPARAGAA
SCHEMBL6548681 0.88 HTT (0.39) HTTFURINL3MBTL1GAA
SCHEMBL7620149 0.88 HTT (0.30) HTT
SCHEMBL6547607 0.87 HTT (0.33) HTT
SCHEMBL6548268 0.86 HTT (0.39) HTTFURINL3MBTL1PPARAGAA
SCHEMBL6547887 0.86 HTT (0.39) HTTFURINL3MBTL1PPARAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 HTT 4052/4885FURIN 3892/4885L3MBTL1 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.