SCHEMBL6547829

SCHEMBL6547829

CON=C(C)c1ccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
FURIN P09958 1/20 0.39
HRH3 Q9Y5N1 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.33
MAPT P10636 2/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
GAA P10253 1/20 0.32
DPP4 P27487 1/20 0.31
LMNA P02545 1/20 0.31
PTPN1 P18031 1/20 0.31
TMPRSS2 O15393 1/20 0.30
PSMB1 P20618 1/20 0.30
PSMB5 P28074 1/20 0.30
PSMB2 P49721 1/20 0.30
PPARG P37231 1/20 0.30
PPARD Q03181 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548268 0.98 HTT (0.39) HTTFURINHRH3L3MBTL1MAPT
SCHEMBL6548442 0.91 HTT (0.39) HTTFURINL3MBTL1MAPTHPGD
SCHEMBL6548681 0.90 HTT (0.39) HTTFURINL3MBTL1MAPTGAA
SCHEMBL6547887 0.89 HTT (0.39) HTTFURINL3MBTL1MAPTGAA
SCHEMBL6548903 0.89 HTT (0.41) HTTFURINL3MBTL1MAPTHPGD
SCHEMBL3964884 0.89 HTT (0.37) HTTFURINL3MBTL1MAPTHPGD
SCHEMBL13606724 0.89 HTT (0.37) HTTFURINL3MBTL1MAPTHPGD
SCHEMBL6547342 0.89 HTT (0.37) HTTFURINL3MBTL1GAAPPARG
SCHEMBL3964886 0.89 HTT (0.37) HTTFURINL3MBTL1MAPTHPGD
SCHEMBL6547431 0.89 HIF1A (0.40) HTTL3MBTL1MAPTHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 HTT 4052/4885FURIN 3892/4885HRH3 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.