SCHEMBL6547708

SCHEMBL6547708

CC(=NOC(C)(C)C)c1cccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)c1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 9/20 0.34
F2 P00734 1/20 0.32
PLG P00747 1/20 0.32
PRSS2 P07478 1/20 0.32
C1S P09871 1/20 0.32
PRSS3 P35030 1/20 0.32
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
HTT P42858 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
HIF1A Q16665 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547342 0.89 HTT (0.37) HTTPPARDPPARA
SCHEMBL6547431 0.89 HIF1A (0.40) PRSS1F2PLGPRSS2C1S
SCHEMBL6548120 0.88 PRSS1 (0.35) PRSS1F2PLGPRSS2C1S
SCHEMBL6549365 0.87 HTT (0.37) HTTPPARDPPARA
SCHEMBL6547981 0.86 PLAU (0.35) PRSS1F2PLGPRSS2C1S
SCHEMBL6548616 0.84 PRSS1 (0.32) PRSS1F2PLGPRSS2C1S
SCHEMBL7620149 0.83 HTT (0.30) HTT
SCHEMBL6548734 0.83 HTT (0.33) HTT
SCHEMBL6547645 0.83 MAOB (0.46) MAOAMAOBHTTKMT2AMEN1
SCHEMBL6547872 0.82 F2 (0.33) F2HTTPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 PRSS1 4480/4885F2 2412/4885PLG 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.