Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | LDHB | P07195 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624112 | 0.87 | PYCR1 (0.42) | CYP3A4CYP2D6TSHRCYP2C19RAB9A | |
| SCHEMBL4442750 | 0.85 | BCL2 (0.54) | CYP3A4CYP2D6TSHRCYP2C19BCL2 | |
| SCHEMBL11323610 | 0.85 | TAAR1 (0.43) | CYP3A4CYP2D6TSHRCYP2C19RAB9A | |
| SCHEMBL8085589 | 0.83 | LTA4H (0.44) | CYP3A4CYP2D6TSHRCYP2C19RAB9A | |
| SCHEMBL29675199 | 0.83 | CALM1 (0.50) | BCL2BCL2L1ALOX5LMNACALM1 | |
| SCHEMBL4455072 | 0.83 | CALM1 (0.50) | BCL2BCL2L1ALOX5LMNACALM1 | |
| SCHEMBL1276089 | 0.83 | CYP3A4 (0.57) | CYP3A4CYP2D6TSHRCYP2C19BCL2 | |
| SCHEMBL8092285 | 0.82 | BCL2 (0.54) | CYP3A4CYP2D6TSHRCYP2C19BCL2 | |
| SCHEMBL3299248 | 0.82 | PYCR1 (0.47) | RAB9ALMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL115910 | 0.82 | RAB9A (0.45) | CYP3A4CYP2D6TSHRCYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | claimed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | claimed |
| EP-0428081-B1 | Method for producing diarylmethanes | KUREHA CHEMICAL IND CO LTD (JP) | 1994-05-04 | — | — | EP | claimed |
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |
| US-5068481-A | Reaction of benzyl chloride with benzene or alkylbenzene in the presence of a zeolite catalyst | KUREHA KAGAKU KOGYO K.K. (JP) | 1991-11-26 | — | — | US | claimed |
| EP-0428081-A1 | Method for producing diarylmethanes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-22 | — | — | EP | claimed |
| US-4390194-A | DYE-PRECURSOR IN SOLVENT MIXTURE OF 1-METHYL-3-PHENYLINDANE AND A DIARYLALKANE | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1983-06-28 | — | — | US | claimed |
| JP-57144235-A | — | — | None | — | — | JP | disclosed |
| US-20220145161-A1 | GREEN COMPOSITIONS FOR USE IN DOWNHOLE AND INDUSTRIAL APPLICATIONS | DELTA-ENERGY GROUP, LLC (US) | 2022-05-12 | — | — | US | disclosed |
| CN-112088200-A | Use of mixtures as dielectric fluids | 阿科玛法国公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-108017557-B | Cyanidation method for preparing nitrile compound | 中国科学院兰州化学物理研究所苏州研究院 | 2020-11-24 | — | — | CN | disclosed |
| US-20150004484-A1 | ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2015-01-01 | — | — | US | disclosed |
| EP-2797153-A1 | ORGANIC ELECTROLYTE, AND ORGANIC ELECTROLYTE STORAGE BATTERY | JX Nippon Oil & Energy Corporation (JP) | 2014-10-29 | — | — | EP | disclosed |
| US-4342739-A | ANTIGEN OR ANTIBODY BOUND MICROCAPSULES | FUJI PHOTO FILM CO., LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| EP-0047998-A1 | Electrically insulating oil composition | Nippon Petrochemicals Co., Ltd. (JP) | 1982-03-24 | — | — | EP | disclosed |
| US-4289806-A | DYE DISSOLVED IN SOLVENT OF AROMATIC HYDROCARBONS HAVING TWO OR THREE NON-CONDENSED BENZENE RINGS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1981-09-15 | — | — | US | disclosed |
| EP-0019363-A1 | Preparation of diphenylmethane derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-11-26 | — | — | EP | disclosed |
| US-4221710-A | PRESSURE SENSITIVE RECORDING SHEET | FUJI PHOTO FILM CO., LTD. (JP) | 1980-09-09 | — | — | US | disclosed |
| US-4219604-A | UREA-FORMALDEHYDE RESIN, CARBOXYLATED POLYVINYL ALCOHOL, HEAT RESISTANT AND NONPERMEABLE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-08-26 | — | — | US | disclosed |
| US-4197417-A | Process for the manufacture of o-benzyl toluenes | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1B, CACNA1C, ORAI1 | CYP3A4 2679/4885CYP2D6 3257/4885TSHR 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.