Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579249 | 0.87 | GABRA1 (0.54) | GABRA1GABRB2HTTGABRG2GABRB3 | |
| SCHEMBL6547447 | 0.87 | HTT (0.48) | GABRA1GABRB2HTTGABRG2GABRB3 | |
| SCHEMBL9579244 | 0.83 | TSHR (0.48) | GABRA1GABRB2HTTGABRG2GABRB3 | |
| SCHEMBL16959756 | 0.83 | GABRA1 (0.40) | GABRA1GABRB2HTTGABRG2GABRB3 | |
| SCHEMBL22558408 | 0.83 | CYP1A2 (0.42) | GABRA1GABRB2HTTGABRG2GABRB3 | |
| SCHEMBL238278 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2HTTGABRG2GABRB3 | |
| SCHEMBL9621059 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2HTTGABRG2GABRB3 | |
| SCHEMBL6546540 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2HTTKCNH2TSHR | |
| SCHEMBL704243 | 0.79 | GABRA1 (0.36) | GABRA1GABRB2HTTGABRG2GABRB3 | |
| SCHEMBL9621062 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2GABRG2GABRB3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316014-B1 | METHOD FOR PRODUCING ARYLETHYLENES | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-4855519-A | Method for producing arylethylene | NIPPON PETROCHEMICALS COMPANY (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0316014-A2 | Method for producing arylethylenes | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-05-17 | — | — | EP | disclosed |
| US-3978143-A | PROCESS FOR PREPARING DIARYLDINITROETHYLENES | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1976-08-31 | — | — | US | disclosed |