SCHEMBL6547524

SCHEMBL6547524

C[SiH](C)CCCc1ccc(F)c(Oc2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.40
LPAR1 Q92633 10/20 0.40
LPAR5 Q9H1C0 10/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10446712 0.83 PPARG (0.45) LPAR1LPAR5
SCHEMBL8638059 0.82 TTR (0.44) TTRLPAR1LPAR5
SCHEMBL10335055 0.81 TTR (0.40) TTRLPAR1LPAR5
SCHEMBL8567112 0.81 TTR (0.40) TTRLPAR1LPAR5
SCHEMBL9804282 0.81 TTR (0.46) TTRLPAR1LPAR5
SCHEMBL14406381 0.81 TTR (0.45) TTRLPAR1LPAR5
SCHEMBL9818509 0.81 CACNA1B (0.45) LPAR1LPAR5
SCHEMBL13888115 0.81 TTR (0.47) TTRLPAR1LPAR5
SCHEMBL10719715 0.78 TTR (0.39) TTRLPAR1LPAR5
SCHEMBL10489467 0.78 TTR (0.42) TTRLPAR1LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004105486-A1 AN INSECTICIDE COMPOSITION FOR INDUSTRIAL HYGIENL AND A WICK FOR USED THEREAL KUKBO PHARMA CO., LTD (KR) 2004-12-09 WO disclosed
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6589914-B2 The dihalopropene compounds of the general formula (I) have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-08 US disclosed
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2003-04-17 US disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-6376710-B2 INSECTICIDES, NEMATODICIDES, MITICIDES SUMITOMO CHEMICAL CO., LTD. (JP) 2002-04-23 US disclosed
EP-0888270-B1 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2002-04-17 EP disclosed
US-20010041740-A1 Amidine compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-11-15 US disclosed
EP-1138668-A2 Amidine compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-10-04 EP disclosed
WO-1993019050-A1 SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO GMBH (DE) 1993-09-30 WO disclosed
EP-0318882-B1 (THIO)BENZOYL UREAS, FUNCTIONAL DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS AND PESTICIDAL USE HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-23 EP disclosed
EP-0535060-A1 ANTIFUNGAL POLYPEPTIDE, PROCESS FOR PRODUCING IT. HOECHST AG (DE) 1993-04-07 EP disclosed
WO-1993006091-A1 SUBSTITUED 4-ALKOXYPYRIMIDINES, A PROCESS FOR PREPARING THE SAME, AGENTS CONTAINING THE SAME AND THEIR USE AS PEST CONTROL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-01 WO disclosed
EP-0534341-A1 4-Alkoxypyrimidin derivatives, process for their preparation, agent containing them and their use as parasiticides Hoechst Schering AgrEvo GmbH (DE) 1993-03-31 EP disclosed
EP-0519211-A1 Substituted 4-aminopyrimidine, process for their preparation and their use as parasiticide Hoechst Schering AgrEvo GmbH (DE) 1992-12-23 EP disclosed
EP-0386715-A2 Heteroaryl-aryl-butene and such butane derivatives, process for their preparation, compositions containing them and their use as biocides Hoechst Schering AgrEvo GmbH (DE) 1990-09-12 EP disclosed
EP-0382112-A2 Pyrimidine trione derivatives, process for their preparation, agents containing them, and their use as parasiticides HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-16 EP disclosed
EP-0325983-A2 N-phenyl benzamides and N-phenyl benzamidoxines, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-02 EP disclosed
EP-0318882-A2 (Thio)benzoyl ureas, functional derivatives, process for their preparation, compositions and pesticidal use HOECHST AKTIENGESELLSCHAFT (DE) 1989-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production DDT, DDC, AADAC TTR 3142/4885LPAR1 2926/4885LPAR5 3658/4885
US-20010041740-A1 Amidine compounds and their use as pesticides DDT, CNR1, PRMT1 TTR 4511/4885LPAR1 1166/4885LPAR5 1377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.