SCHEMBL2487952

SCHEMBL2487952

C[Si](C)(C)O[Si](C)(C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12136745 0.96 ESR1 (0.34) ESR1ESR2
SCHEMBL339880 0.91 ESR1 (0.39) ESR1ESR2
SCHEMBL6547160 0.89 ESR1 (0.38) ESR1ESR2
SCHEMBL6546676 0.89 ESR1 (0.38) ESR1ESR2
SCHEMBL6547559 0.89 ESR1 (0.38) ESR1ESR2
SCHEMBL18094270 0.88 ESR1 (0.32) ESR1ESR2
SCHEMBL12136768 0.83
SCHEMBL26973343 0.81 ESR1 (0.33) ESR1ESR2
SCHEMBL9715929 0.80 ESR1 (0.35) ESR1ESR2
SCHEMBL22660801 0.80 ESR1 (0.35) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620068-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2006-02-01 EP claimed
WO-2004087077-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2004-10-14 WO claimed
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US claimed
EP-3558222-B1 WATER-IN-OIL EMULSION COMPRISING A PARTICULAR EMULSIFYING SYSTEM, A LIPOPHILIC CLAY, AND AN ORGANOPOLYSILOXANE ELASTOMER POWDER COATED WITH A SILICONE RESIN OREAL (FR) 2024-04-03 EP disclosed
EP-3558238-B1 COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE, A LIQUID DIPHENYLACRYLATE UV-SCREENING AGENT, A LIQUID SALICYLATE UV-SCREENING AGENT AND A NON-CYCLIC VOLATILE SILICONE OIL OREAL (FR) 2023-08-23 EP disclosed
CN-110087609-B Water-in-oil emulsion containing baicalin, xanthine base, vitamin B3, and polyvalent metal cation salt 莱雅公司 2022-11-15 CN disclosed
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt L'OREAL (FR) 2022-07-05 US disclosed
CN-110099662-B Water-in-oil emulsion comprising a specific emulsifying system, a lipophilic clay and a silicone resin-coated organopolysiloxane elastomer powder 莱雅公司 2022-04-26 CN disclosed
EP-3558216-B1 WATER-IN-OIL EMULSION CONTAINING BAICALIN, A XANTHINE BASE, A VITAMIN B3, AND A POLYVALENT METAL CATION SALT L'ORÉAL (FR) 2020-09-16 EP disclosed
US-10653600-B2 Cosmetic composition comprising a supramolecular compound capable of establishing hydrogen bonds, and two particular distinct silicone oils L'OREAL (FR) 2020-05-19 US disclosed
US-20200085723-A1 COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE, A LIQUID beta,beta-DIPHENYLACRYLATE UV-SCREENING AGENT, A LIQUID SALICYLATE UV-SCREENING AGENT AND A NON-CYCLIC VOLATILE SILICONE OIL L'OREAL (FR) 2020-03-19 US disclosed
US-20130136705-A1 COSMETIC COMPOSITION COMPRISING AN OIL AND A POLYMER BOTH BEARING A HYDROGEN-BOND-GENERATING JOINING GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2013-05-30 US disclosed
US-8440211-B2 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2013-05-14 US disclosed
US-20120234196-A1 Viscous Liquid Monopropellant PLANETARY SYSTEMS CORPORATION 2012-09-20 US disclosed
EP-1620068-B1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE OREAL (FR) 2012-05-09 EP disclosed
EP-2380556-A1 Cosmetic composition comprising a volatile fatty phase L'Oréal (FR) 2011-10-26 EP disclosed
US-20090074689-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL S.A. 2009-03-19 US disclosed
EP-1620068-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2006-02-01 EP disclosed
WO-2004087077-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2004-10-14 WO disclosed
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10653600-B2 Cosmetic composition comprising a supramolecular compound capable of establishing hydrogen bonds, and two particular distinct silicone oils CHEK1, STIM1, FASN ESR1 1919/4885ESR2 3623/4885
US-20130136705-A1 COSMETIC COMPOSITION COMPRISING AN OIL AND A POLYMER BOTH BEARING A HYDROGEN-BOND-GENERATING JOINING GROUP, AND COSMETIC TREATMENT PROCESS SQLE, MMS19, FDFT1 ESR1 3072/4885ESR2 3880/4885
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt KRT18, BROX, S100B ESR1 4223/4885ESR2 4346/4885
US-20200085723-A1 COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE, A LIQUID beta,beta-DIPHENYLACRYLATE UV-SCREENING AGENT, A LIQUID SALICYLATE UV-SCREENING AGENT AND A NON-CYCLIC VOLATILE SILICONE OIL KRT18, CUTA, SKP1 ESR1 3821/4885ESR2 3585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.