SCHEMBL6547645

SCHEMBL6547645

CC(=O)c1cccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.46
MAOA P21397 3/20 0.46
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8895257 0.90 KMT2A (0.49) KMT2ARAB9A
SCHEMBL6547877 0.87 L3MBTL1 (0.51) MAOBMAOAKMT2AALDH1A1HTT
SCHEMBL6547431 0.85 HIF1A (0.40) MAOBMAOAKMT2AMEN1HTT
SCHEMBL6548648 0.85 L3MBTL1 (0.55) MAOBMAOAALDH1A1HTTSMN1; SMN2
SCHEMBL6548120 0.84 PRSS1 (0.35) MAOBMAOAKMT2AMEN1HTT
SCHEMBL6549409 0.84 GAA (0.56) MAOBMAOAALDH1A1HTTSMN1; SMN2
SCHEMBL8659537 0.84 MAPK1 (0.41) KMT2AALDH1A1HTTSMN1; SMN2
SCHEMBL8661858 0.84 MAPK1 (0.47) KMT2AMEN1ALDH1A1
SCHEMBL6547959 0.84 HTT (0.49) MAOBMAOAALDH1A1HTTSMN1; SMN2
SCHEMBL8658605 0.83 PPARG (0.44) MAOBKMT2AHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 MAOB 1041/4885MAOA 944/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.