SCHEMBL6547431

SCHEMBL6547431

CON=C(C)c1cccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.40
PRSS1 P07477 9/20 0.36
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
F2 P00734 1/20 0.34
PLG P00747 1/20 0.34
PRSS2 P07478 1/20 0.34
C1S P09871 1/20 0.34
PRSS3 P35030 1/20 0.34
MAPT P10636 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
MAPK1 P28482 2/20 0.33
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548120 0.91 PRSS1 (0.35) PRSS1F2PLGPRSS2C1S
SCHEMBL6547981 0.89 PLAU (0.35) HIF1APRSS1F2PLGPRSS2
SCHEMBL6547708 0.89 PRSS1 (0.34) HIF1APRSS1NPC1RAB9AF2
SCHEMBL6547829 0.89 HTT (0.39) MAPTMAPK1HPGDL3MBTL1HTT
SCHEMBL6548616 0.87 PRSS1 (0.32) PRSS1F2PLGPRSS2C1S
SCHEMBL6548268 0.86 HTT (0.39) PRSS1NPC1RAB9AMAPTL3MBTL1
SCHEMBL6547645 0.85 MAOB (0.46) RAB9ASMN1; SMN2MAOAMAOBHTT
SCHEMBL8661858 0.82 MAPK1 (0.47) MAPTMAPK1HPGDL3MBTL1MEN1
SCHEMBL6547987 0.82 PPARA (0.41) NPC1RAB9AF2MAPTMAPK1
SCHEMBL7619271 0.82 MAPT (0.32) MAPTMAPK1HPGDL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 HIF1A 1262/4885PRSS1 4480/4885NPC1 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.