Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548444 | 0.83 | POLB (0.47) | CYP3A4CYP2C19TSHRKMT2AMEN1 | |
| SCHEMBL6549109 | 0.74 | LMNA (0.44) | CYP3A4CYP2C19TSHRKMT2AALDH1A1 | |
| SCHEMBL6547904 | 0.72 | MEN1 (0.48) | CYP3A4CYP2C19TSHRKMT2AMEN1 | |
| SCHEMBL6549283 | 0.72 | SMN1; SMN2 (0.45) | CYP3A4CYP2C19TSHRKMT2AMEN1 | |
| SCHEMBL6548091 | 0.71 | CYP3A4 (0.48) | CYP3A4CYP2C19TSHRHTTKMT2A | |
| SCHEMBL6548105 | 0.71 | CYP3A4 (0.48) | CYP3A4CYP2C19TSHRHTTKMT2A | |
| SCHEMBL6547253 | 0.68 | KMT2A (0.44) | CYP3A4CYP2C19TSHRKMT2AMEN1 | |
| SCHEMBL6548227 | 0.66 | LMNA (0.45) | CYP3A4CYP2C19TSHRKMT2AMEN1 | |
| SCHEMBL6549347 | 0.66 | MEN1 (0.43) | CYP3A4CYP2C19TSHRKMT2AMEN1 | |
| SCHEMBL6549071 | 0.66 | KMT2A (0.41) | CYP3A4CYP2C19TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1106609-B1 | Aminoalcohol derivative and medicament comprising the same | SEIKAGAKU KOGYO CO LTD (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-6407064-B2 | A MORPHOLINO RING CONTAINING ALKYLAMINOALCOHOL DERIVATIVE OR SALTS USEFUL FOR TREATING NEURONAL DISEASES AND AN AGENT FOR PROTECTING BRAIN | SEIKAGAKU CORPORATION (JP) | 2002-06-18 | — | — | US | disclosed |
| US-20010003741-A1 | Aminoalcohol derivative and medicament comprising the same | SEIKAGAKU CORPORATION (JP) | 2001-06-14 | — | — | US | disclosed |
| EP-1106609-A2 | Aminoalcohol derivative and medicament comprising the same | SEIKAGAKU CORPORATION (JP) | 2001-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003741-A1 | Aminoalcohol derivative and medicament comprising the same | SGMS2, FABP7, SGMS1 | CYP3A4 4788/4885CYP2C19 4868/4885TSHR 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.