Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548063 | 0.74 | RAPGEF4 (0.47) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL21117641 | 0.72 | CA1 (0.56) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL2047218 | 0.72 | RAPGEF4 (0.67) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL9803133 | 0.71 | F2 (0.61) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7458962 | 0.70 | ALDH1A1 (0.36) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL330754 | 0.70 | CA1 (0.54) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL8271353 | 0.70 | CA1 (0.54) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL14516136 | 0.70 | F2 (0.59) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL31066637 | 0.70 | CA1 (0.53) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL16140087 | 0.70 | F2 (0.53) | F2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1162962-A4 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1162962-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2001-12-19 | — | — | EP | disclosed |
| US-6232503-B1 | MICROBIOCIDES | LONZA INC. | 2001-05-15 | — | — | US | disclosed |
| WO-2000056305-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2000-09-28 | — | — | WO | disclosed |