Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562311 | 0.89 | ELANE (0.39) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL6548536 | 0.87 | ELANE (0.44) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL6549016 | 0.85 | MAPT (0.47) | KMT2AL3MBTL1TSHRLMNACYP1A2 | |
| SCHEMBL6393368 | 0.83 | TSHR (0.44) | ELANEKMT2ASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6393362 | 0.83 | TSHR (0.44) | ELANEKMT2ASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6547272 | 0.82 | PDCD1 (0.44) | KMT2ASMN1; SMN2L3MBTL1TSHRTP53 | |
| SCHEMBL6387977 | 0.80 | HSD17B10 (0.50) | ELANEKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6547911 | 0.80 | MAPT (0.42) | KMT2ATDP1L3MBTL1TSHRMEN1 | |
| SCHEMBL12036573 | 0.78 | TSHR (0.42) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL10341104 | 0.78 | TSHR (0.40) | ELANEKMT2AHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730371-B2 | LIQUID CRYSTAL DISPLAY | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-05-04 | — | — | US | disclosed |
| EP-1249484-B1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-20030054119-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO., INC. | 2003-03-20 | — | — | US | disclosed |
| EP-1249484-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030054119-A1 | Optically active compound and liquid crystal composition containing the compound | HDHD5, THOC2, TDO2 | ELANE 2874/4885KMT2A 3725/4885HTT 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.