Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170147 | 0.93 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL97778 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL19257635 | 0.75 | — | — | |
| SCHEMBL18665263 | 0.73 | — | — | |
| SCHEMBL14775080 | 0.73 | TSHR (0.39) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL361130 | 0.72 | — | — | |
| SCHEMBL31506420 | 0.69 | ALDH1A1 (0.33) | ALDH1A1TDP1TSHRESR1MAPT | |
| SCHEMBL2991686 | 0.69 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL10107013 | 0.68 | TSHR (0.62) | ALDH1A1TDP1TSHRMAPTHSD17B10 | |
| SCHEMBL18481189 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290679-B2 | Water based rubber cement and tire with fabricated tread | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2016-03-22 | — | — | US | claimed |
| US-20140202607-A1 | WATER BASED RUBBER CEMENT AND TIRE WITH FABRICATED TREAD | GOODYEAR TIRE & RUBBER COMPANY, THE | 2014-07-24 | — | — | US | claimed |
| EP-1191057-B1 | Silica reinforced rubber composition prepared with pretreated silica and article of manufacture | GOODYEAR TIRE & RUBBER (US) | 2004-12-01 | — | — | EP | claimed |
| US-6713549-B1 | UTILIZING NONALKOXYSILANE CONTAINING COUPLING AGENT; REDUCED ALCOHOL BYPRODUCT EVOLUTION | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-03-30 | — | — | US | claimed |
| EP-1191057-A1 | Silica reinforced rubber composition prepared with pretreated silica and article of manufacture | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-03-27 | — | — | EP | claimed |
| EP-0791623-B1 | Silica reinforced rubber composition and tire with tread thereof | GOODYEAR TIRE & RUBBER (US) | 1999-12-01 | — | — | EP | claimed |
| EP-0791623-A1 | Silica reinforced rubber composition and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-08-27 | — | — | EP | claimed |
| US-5605951-A | SILICA COUPLER IS A 3,3'-TETRATHIODIPROPIONITRILE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-02-25 | — | — | US | claimed |
| JP-9227722-A | — | — | None | — | — | JP | disclosed |
| US-9290679-B2 | Water based rubber cement and tire with fabricated tread | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2016-03-22 | — | — | US | disclosed |
| US-20140202619-A1 | ADHESIVE BONDING FOR A PNEUMATIC TIRE | The Goodvear Tire & Rubber Company (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140202607-A1 | WATER BASED RUBBER CEMENT AND TIRE WITH FABRICATED TREAD | GOODYEAR TIRE & RUBBER COMPANY, THE | 2014-07-24 | — | — | US | disclosed |
| EP-1191057-B1 | Silica reinforced rubber composition prepared with pretreated silica and article of manufacture | GOODYEAR TIRE & RUBBER (US) | 2004-12-01 | — | — | EP | disclosed |
| US-6713549-B1 | UTILIZING NONALKOXYSILANE CONTAINING COUPLING AGENT; REDUCED ALCOHOL BYPRODUCT EVOLUTION | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-03-30 | — | — | US | disclosed |
| EP-0791623-B1 | Silica reinforced rubber composition and tire with tread thereof | GOODYEAR TIRE & RUBBER (US) | 1999-12-01 | — | — | EP | disclosed |
| JP-H09227722-A | SILICA-REINFORCED RUBBER COMPOSITION AND TIRE HAVING ITS TREAD | GOODYEAR TIRE & RUBBER CO:THE | 1997-09-02 | — | — | JP | disclosed |
| EP-0791623-A1 | Silica reinforced rubber composition and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-08-27 | — | — | EP | disclosed |
| EP-0791623-A1 | Silica reinforced rubber composition and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5605951-A | SILICA COUPLER IS A 3,3'-TETRATHIODIPROPIONITRILE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| US-5605951-A | SILICA COUPLER IS A 3,3'-TETRATHIODIPROPIONITRILE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-02-25 | — | — | US | disclosed |