SCHEMBL6548349

SCHEMBL6548349

CCCCC1C(c2ccccc2)=CC=CC1(C)C

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
NR1H3 Q13133 1/20 0.33
HSD11B1 P28845 2/20 0.31
CNR2 P34972 1/20 0.30
CHRM2 P08172 2/20 0.30
CHRM4 P08173 2/20 0.30
CHRM5 P08912 2/20 0.30
CHRM1 P11229 2/20 0.30
CHRM3 P20309 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547131 0.72 OPRM1 (0.31)
SCHEMBL4661816 0.68 CHRM2 (0.33) TSHRCHRM2CHRM4CHRM5CHRM1
SCHEMBL4661320 0.64 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL31211826 0.62 CRHBP (0.34)
SCHEMBL258077 0.62 CACNA1B (0.31)
SCHEMBL27364151 0.61 ALDH1A1 (0.43) TSHRHSD11B1
SCHEMBL21698511 0.61 MAOB (0.32)
Biphenyl SCHEMBL15347228 0.61 ALDH1A1 (0.56) TSHRHSD11B1
Biphenyl SCHEMBL5868585 0.61 ALDH1A1 (0.56) TSHRNR1H3HSD11B1
Biphenyl SCHEMBL16196748 0.59 ALDH1A1 (0.53) TSHRNR1H3HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
CN-1109679-C Dihydrobenzofuran and related compounds useful as anti-inflammatory agents UNIV VANDERBILT (US) 2003-05-28 CN disclosed
CN-1072668-C Dihydrobenzofuran and related compounds useful as anti-inflammatory agents VANDEBERT UNIV (US) 2001-10-10 CN disclosed
CN-1210531-A Dihydrobenzofuran and related compounds useful as anti-inflammatory agents PROCTER & GAMBLE (US) 1999-03-10 CN disclosed
CN-1210534-A Dihydrobenzofuran and related compounds useful as anti-inflammatory agents PROCTER & GAMBLE (US) 1999-03-10 CN disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed