SCHEMBL6548371

SCHEMBL6548371

CC(C)ON=Cc1ccc(OCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ORAI1 Q96D31 1/20 0.34
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 2/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
FAAH O00519 2/20 0.30
GCGR P47871 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548304 0.97 L3MBTL1 (0.36) HTTPPARGPPARAL3MBTL1MEN1
SCHEMBL6548013 0.97 L3MBTL1 (0.36) HTTPPARGPPARAL3MBTL1MEN1
SCHEMBL6548693 0.97 L3MBTL1 (0.36) HTTPPARGPPARAL3MBTL1MEN1
SCHEMBL6548306 0.97 L3MBTL1 (0.36) HTTPPARGPPARAL3MBTL1MEN1
SCHEMBL6548813 0.96 L3MBTL1 (0.36) HTTPPARGPPARAL3MBTL1MEN1
SCHEMBL6549314 0.91 ORAI1 (0.36) HTTL3MBTL1MEN1KMT2AORAI1
SCHEMBL6549320 0.91 ORAI1 (0.36) HTTL3MBTL1MEN1KMT2AORAI1
SCHEMBL6549961 0.90 PPARG (0.35) HTTPPARGPPARALMNAPOLB
SCHEMBL6549649 0.89 PPARG (0.34) HTTPPARGPPARAL3MBTL1MEN1
SCHEMBL6548372 0.88 HTT (0.38) HTTPPARGPPARAL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 HTT 4052/4885PPARG 2821/4885PPARA 2987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.