SCHEMBL6548372

SCHEMBL6548372

CO/N=C/c1ccc(OCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
SRC P12931 1/20 0.35
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
ORAI1 Q96D31 1/20 0.32
FAAH O00519 2/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548375 1.00 HTT (0.38) HTTMEN1KMT2AL3MBTL1SRC
SCHEMBL6548443 0.97 L3MBTL1 (0.38) HTTMEN1KMT2AL3MBTL1SRC
SCHEMBL6549580 0.97 L3MBTL1 (0.38) HTTMEN1KMT2AL3MBTL1SRC
SCHEMBL6549585 0.97 L3MBTL1 (0.38) HTTMEN1KMT2AL3MBTL1SRC
SCHEMBL6548439 0.97 L3MBTL1 (0.38) HTTMEN1KMT2AL3MBTL1SRC
SCHEMBL6547430 0.96 L3MBTL1 (0.38) HTTMEN1KMT2AL3MBTL1MAPT
SCHEMBL6547435 0.96 L3MBTL1 (0.38) HTTMEN1KMT2AL3MBTL1MAPT
SCHEMBL6548281 0.90 L3MBTL1 (0.42) HTTMEN1KMT2AL3MBTL1MAPT
SCHEMBL6548278 0.90 L3MBTL1 (0.42) HTTMEN1KMT2AL3MBTL1MAPT
SCHEMBL6547908 0.89 L3MBTL1 (0.40) HTTMEN1KMT2AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 HTT 4052/4885MEN1 4425/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.