SCHEMBL6548439

SCHEMBL6548439

CO/N=C/c1ccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
SRC P12931 1/20 0.35
GAA P10253 2/20 0.34
FAAH O00519 3/20 0.33
MAPK1 P28482 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548443 1.00 L3MBTL1 (0.38) L3MBTL1MEN1KMT2AHTTMAPT
SCHEMBL6549580 0.98 L3MBTL1 (0.38) L3MBTL1MEN1KMT2AHTTMAPT
SCHEMBL6549585 0.98 L3MBTL1 (0.38) L3MBTL1MEN1KMT2AHTTMAPT
SCHEMBL6547430 0.97 L3MBTL1 (0.38) L3MBTL1MEN1KMT2AHTTMAPT
SCHEMBL6547435 0.97 L3MBTL1 (0.38) L3MBTL1MEN1KMT2AHTTMAPT
SCHEMBL6548375 0.97 HTT (0.38) L3MBTL1MEN1KMT2AHTTMAPT
SCHEMBL6548372 0.97 HTT (0.38) L3MBTL1MEN1KMT2AHTTMAPT
SCHEMBL6548218 0.90 L3MBTL1 (0.43) L3MBTL1MEN1KMT2AHTTMAPT
SCHEMBL6548216 0.90 L3MBTL1 (0.43) L3MBTL1MEN1KMT2AHTTMAPT
SCHEMBL6549167 0.89 L3MBTL1 (0.41) L3MBTL1MEN1KMT2AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 L3MBTL1 876/4885MEN1 4425/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.