SCHEMBL6548446

SCHEMBL6548446

ClC(Cl)=CCO/N=C/c1ccc(COc2c(Cl)cc(OCC=C(Br)Br)cc2Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.36
MEN1 O00255 7/20 0.36
MAPT P10636 5/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 3/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPSR1 Q6W5P4 2/20 0.34
NPC1 O15118 6/20 0.33
RAB9A P51151 6/20 0.33
KDM4E B2RXH2 2/20 0.33
CCR5 P51681 1/20 0.33
CCR6 P51684 1/20 0.33
UBE2N P61088 1/20 0.33
SMN1; SMN2 Q16637 5/20 0.32
NFKB1 P19838 2/20 0.32
NFKB2 Q00653 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548450 1.00 KMT2A (0.36) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL6548054 0.95 KMT2A (0.40) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL6548050 0.95 KMT2A (0.40) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL6548646 0.88 KMT2A (0.37) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL6548649 0.88 KMT2A (0.37) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL6548380 0.88 L3MBTL1 (0.39) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL6548386 0.88 L3MBTL1 (0.39) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL6549508 0.87 KMT2A (0.38) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL6549505 0.87 KMT2A (0.38) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL6548778 0.87 L3MBTL1 (0.40) KMT2AMEN1MAPTL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 KMT2A 2985/4885MEN1 4425/4885MAPT 4623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.