SCHEMBL6548907

SCHEMBL6548907

CCON=C(CC)c1ccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
ORAI1 Q96D31 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
GAA P10253 1/20 0.31
RAB9A P51151 1/20 0.31
MCL1 Q07820 1/20 0.31
DPP4 P27487 1/20 0.31
ALDH1A1 P00352 2/20 0.30
FURIN P09958 1/20 0.30
PLA2G4B P0C869 1/20 0.30
NR1I2 O75469 1/20 0.30
KDM4E B2RXH2 2/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549172 0.91 GAA (0.34) L3MBTL1MAPTTHRBHTTFFAR1
SCHEMBL6547608 0.89 GAA (0.37) L3MBTL1MAPTTHRBHTTORAI1
SCHEMBL6548681 0.88 HTT (0.39) L3MBTL1MAPTHTTFFAR1FFAR4
SCHEMBL6548797 0.87 GAA (0.38) L3MBTL1MAPTTHRBHTTORAI1
SCHEMBL6548194 0.86 MAPT (0.33) L3MBTL1MAPTTHRBHTTORAI1
SCHEMBL6548597 0.86 HTT (0.39) L3MBTL1MAPTHTTFFAR1FFAR4
SCHEMBL6547432 0.86 GAA (0.39) L3MBTL1MAPTTHRBHTTORAI1
SCHEMBL6548348 0.86 ALDH1A1 (0.36) L3MBTL1MAPTHTTALDH1A1KDM4E
SCHEMBL6548310 0.85 HTT (0.38) L3MBTL1MAPTHTTGAARAB9A
SCHEMBL6549633 0.85 HTT (0.38) L3MBTL1MAPTHTTGAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 L3MBTL1 876/4885MAPT 4623/4885THRB 1780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.