SCHEMBL6549172

SCHEMBL6549172

CCCCC(=NOCC)c1ccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.34
RAB9A P51151 2/20 0.34
HTT P42858 1/20 0.34
SLC6A4 P31645 3/20 0.34
PLA2G4B P0C869 1/20 0.33
DPP4 P27487 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
TP53 P04637 2/20 0.32
LMNA P02545 2/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
TSHR P16473 1/20 0.32
THRA P10827 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548907 0.91 L3MBTL1 (0.36) GAARAB9AHTTPLA2G4BDPP4
SCHEMBL6548681 0.86 HTT (0.39) GAARAB9AHTTPLA2G4BDPP4
SCHEMBL6548597 0.84 HTT (0.39) GAARAB9AHTTL3MBTL1FFAR1
SCHEMBL6549311 0.84 L3MBTL1 (0.50) HTTPLA2G4BL3MBTL1LMNANPC1
SCHEMBL6548348 0.83 ALDH1A1 (0.36) HTTSLC6A4L3MBTL1LMNAMAPT
SCHEMBL6548310 0.83 HTT (0.38) GAARAB9AHTTPLA2G4BL3MBTL1
SCHEMBL6549633 0.83 HTT (0.38) GAARAB9AHTTPLA2G4BL3MBTL1
SCHEMBL6547864 0.83 HTT (0.39) GAARAB9AHTTL3MBTL1FFAR1
SCHEMBL6547608 0.83 GAA (0.37) GAARAB9AHTTPLA2G4BDPP4
SCHEMBL6547985 0.82 HTT (0.34) HTTFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed