Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455027 | 0.82 | HSD11B1 (0.39) | KDM4EALDH1A1SMN1; SMN2HSD11B1ACHE | |
| SCHEMBL7484680 | 0.80 | CES2 (0.32) | CES2CES1RIPK1 | |
| SCHEMBL6548754 | 0.78 | REV1 (0.37) | REV1CES2BCHECES1HTR2C | |
| SCHEMBL1547936 | 0.75 | REV1 (0.43) | REV1CES2BCHECES1HTR2C | |
| SCHEMBL22637692 | 0.74 | REV1 (0.60) | REV1CES2BCHECES1HTR2C | |
| SCHEMBL6549651 | 0.74 | REV1 (0.37) | REV1CES2BCHECES1HTR2C | |
| SCHEMBL5263526 | 0.72 | PBRM1 (0.43) | CES2CES1KDM4EALDH1A1 | |
| SCHEMBL9074582 | 0.72 | REV1 (0.44) | REV1CES2BCHECES1HTR2C | |
| SCHEMBL14297801 | 0.70 | CES2 (0.43) | REV1CES2BCHECES1HTR2C | |
| Alcohol SCHEMBL27924880 | 0.69 | CES2 (0.46) | CES2BCHECES1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366026-B1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |