Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318596 | 0.90 | TP53 (0.42) | TP53CALM1CHKAALDH1A1TSHR | |
| SCHEMBL368538 | 0.87 | CHKA (0.40) | TP53CALM1CHKAALDH1A1TSHR | |
| SCHEMBL5100518 | 0.85 | TP53 (0.39) | TP53CALM1CHKAALDH1A1TSHR | |
| SCHEMBL11155177 | 0.84 | SIGMAR1 (0.44) | TP53CALM1ALDH1A1TSHRSIGMAR1 | |
| SCHEMBL348590 | 0.80 | ALDH1A1 (0.39) | TP53ALDH1A1TSHR | |
| SCHEMBL349052 | 0.77 | GBA1 (0.39) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2220376 | 0.73 | ALDH1A1 (0.32) | TP53CALM1CHKAALDH1A1TSHR | |
| SCHEMBL6551146 | 0.70 | SIGMAR1 (0.47) | ALDH1A1IDO1SMN1; SMN2SIGMAR1HPGD | |
| SCHEMBL13283227 | 0.69 | CHKA (0.61) | TP53CHKAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL93665 | 0.67 | CHKA (0.59) | CHKAALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014999-B1 | CATIONIC POLYMERS AS TOXIN-BINDING AGENTS | GENZYME CORP (US) | 2004-12-08 | — | — | EP | claimed |