Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.55 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9995332 | 0.77 | KMO (0.59) | ACLYKMOHTR7MCL1PRMT5 | |
| SCHEMBL8430623 | 0.74 | KMO (0.59) | ACLYKMOHTR7MCL1CDK4 | |
| SCHEMBL13668162 | 0.74 | KMO (0.56) | ACLYKMOHTR7MCL1PRMT5 | |
| SCHEMBL8430621 | 0.70 | KMO (0.62) | ACLYKMOHTR7MCL1PRMT5 | |
| SCHEMBL7676168 | 0.70 | HTR2C (0.55) | ACLYKMOHTR7PRMT5OXER1 | |
| SCHEMBL7676174 | 0.70 | HTR2C (0.55) | ACLYKMOHTR7PRMT5OXER1 | |
| SCHEMBL10311228 | 0.67 | KMO (0.57) | ACLYKMOHTR7MCL1PRMT5 | |
| SCHEMBL15723822 | 0.67 | SLC6A2 (0.43) | KMOHTR7PRMT5SLC6A2SLC6A4 | |
| SCHEMBL22421046 | 0.67 | HTR7 (0.60) | KMOHTR7 | |
| SCHEMBL24144837 | 0.66 | HTR2C (0.58) | KMOHTR7PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480966-A1 | COMPOUNDS AND METHODS OF TREATING CELL PROLIFERATIVE DISEASES | Exonhit Therapeutics S.A. (FR) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074508-A1 | COMPOUNDS AND METHODS OF TREATING CELL PROLIFERATIVE DISEASES | EXONHIT THERAPEUTICS SA (FR) | 2003-09-12 | — | — | WO | disclosed |