SCHEMBL6551075

SCHEMBL6551075

CC(CC1CC2C=CC1C2)(C(=O)O)C1CCC(=O)CC1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.35
ALDH1A1 P00352 6/20 0.34
TDP1 Q9NUW8 3/20 0.34
PKM P14618 3/20 0.32
MAPK1 P28482 2/20 0.32
MAPT P10636 2/20 0.31
TSHR P16473 1/20 0.31
POLB P06746 1/20 0.31
ALOX15 P16050 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6550594 0.85 KDM4E (0.37) KDM4EALDH1A1TDP1PKMMAPK1
SCHEMBL6548933 0.84 KDM4E (0.36) KDM4EALDH1A1TDP1PKMMAPK1
SCHEMBL6549460 0.84 KDM4E (0.36) KDM4EALDH1A1TDP1PKMMAPK1
SCHEMBL196728 0.74 KDM4E (0.43) KDM4EALDH1A1TDP1PKMMAPK1
SCHEMBL13346658 0.69 KDM4E (0.41) KDM4EALDH1A1TDP1PKMMAPK1
SCHEMBL6551067 0.68
SCHEMBL525477 0.68 ALDH1A1 (0.38) KDM4EALDH1A1TDP1MAPK1POLB
SCHEMBL15803193 0.67 KDM4E (0.43) KDM4EALDH1A1TDP1TSHRPOLB
SCHEMBL12357865 0.67 KDM4E (0.43) KDM4EALDH1A1TDP1TSHRPOLB
SCHEMBL15466780 0.67 KDM4E (0.46) KDM4EALDH1A1TDP1TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1167349-B1 Chemical amplifying type positive resist composition SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6548220-B2 Containing acid generator SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-15 US disclosed