Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197302 | 0.80 | TDP1 (0.37) | TAAR1ALDH1A1TDP1THRBTP53 | |
| SCHEMBL10225708 | 0.78 | MAPT (0.37) | TAAR1MAPTALDH1A1POLBRXFP1 | |
| SCHEMBL9814744 | 0.77 | NQO2 (0.40) | MAPTALDH1A1POLBHPGDTP53 | |
| SCHEMBL7634615 | 0.77 | HPGD (0.36) | TAAR1MAPTALDH1A1POLBRXFP1 | |
| SCHEMBL146113 | 0.76 | AMY1A (0.37) | TAAR1MAPTALDH1A1POLBRXFP1 | |
| SCHEMBL7187263 | 0.76 | MAPT (0.36) | TAAR1MAPTALDH1A1POLBRXFP1 | |
| Hydrochloric Acid SCHEMBL30471359 | 0.74 | AMY1A (0.36) | TAAR1MAPTALDH1A1POLBRXFP1 | |
| SCHEMBL2157219 | 0.74 | AMY1A (0.36) | TAAR1MAPTALDH1A1POLBRXFP1 | |
| SCHEMBL22892211 | 0.74 | ALDH1A1 (0.34) | MAPTALDH1A1TDP1THRBGAA | |
| SCHEMBL9221189 | 0.74 | MGLL (0.39) | MAPTALDH1A1GPR55HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480987-A1 | COVALENTLY FIXED NON-METALLOCENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR POLYMERIZING OLEFINS | Celanese Ventures GmbH (DE) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072584-A1 | COVALENTLY FIXED NON-METALLOCENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-09-04 | — | — | WO | disclosed |