Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549347 | 0.89 | MEN1 (0.43) | KMT2AMEN1CYP3A4CYP2C19MAPT | |
| SCHEMBL6548271 | 0.88 | KMT2A (0.45) | KMT2AMEN1CYP3A4CYP2C19MAPT | |
| SCHEMBL6549353 | 0.81 | MEN1 (0.44) | KMT2AMEN1CYP3A4CYP2C19MAPT | |
| SCHEMBL6548227 | 0.79 | LMNA (0.45) | KMT2AMEN1CYP3A4CYP2C19MAPT | |
| SCHEMBL6549071 | 0.73 | KMT2A (0.41) | KMT2AMEN1CYP3A4CYP2C19MAPT | |
| SCHEMBL6549109 | 0.70 | LMNA (0.44) | KMT2ACYP3A4CYP2C19MAPTLMNA | |
| SCHEMBL6548444 | 0.70 | POLB (0.47) | KMT2AMEN1CYP3A4CYP2C19MAPT | |
| SCHEMBL6547904 | 0.69 | MEN1 (0.48) | KMT2AMEN1CYP3A4CYP2C19MAPT | |
| SCHEMBL6549283 | 0.68 | SMN1; SMN2 (0.45) | KMT2AMEN1CYP3A4CYP2C19MAPT | |
| SCHEMBL6547253 | 0.66 | KMT2A (0.44) | KMT2AMEN1CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1106609-B1 | Aminoalcohol derivative and medicament comprising the same | SEIKAGAKU KOGYO CO LTD (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-6407064-B2 | A MORPHOLINO RING CONTAINING ALKYLAMINOALCOHOL DERIVATIVE OR SALTS USEFUL FOR TREATING NEURONAL DISEASES AND AN AGENT FOR PROTECTING BRAIN | SEIKAGAKU CORPORATION (JP) | 2002-06-18 | — | — | US | disclosed |
| US-20010003741-A1 | Aminoalcohol derivative and medicament comprising the same | SEIKAGAKU CORPORATION (JP) | 2001-06-14 | — | — | US | disclosed |
| EP-1106609-A2 | Aminoalcohol derivative and medicament comprising the same | SEIKAGAKU CORPORATION (JP) | 2001-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003741-A1 | Aminoalcohol derivative and medicament comprising the same | SGMS2, FABP7, SGMS1 | KMT2A 2489/4885MEN1 2933/4885CYP3A4 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.