SCHEMBL6550438

SCHEMBL6550438

NCCCn1c2ccccc2c2cc(N)ccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.64
HPGD P15428 3/20 0.64
KDM4E B2RXH2 2/20 0.64
ALDH1A1 P00352 2/20 0.64
MEN1 O00255 1/20 0.64
MAPT P10636 1/20 0.64
MAPK1 P28482 1/20 0.64
HTT P42858 1/20 0.64
HBB P68871 1/20 0.64
KMT2A Q03164 1/20 0.64
HSD17B10 Q99714 1/20 0.64
SIGMAR1 Q99720 1/20 0.59
RXRA P19793 2/20 0.47
FABP4 P15090 2/20 0.45
FABP5 Q01469 2/20 0.45
GLA P06280 1/20 0.44
APEX1 P27695 1/20 0.44
SYK P43405 1/20 0.44
RECQL P46063 1/20 0.44
MAOA P21397 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8516923 0.98 TDP1 (0.62) TDP1HPGDKDM4EALDH1A1MEN1
SCHEMBL7407425 0.86 FABP4 (0.56) TDP1HPGDKDM4ESIGMAR1FABP4
SCHEMBL31739343 0.86 ALDH1A1 (0.71) TDP1HPGDKDM4EALDH1A1MEN1
SCHEMBL10945941 0.86 ALDH1A1 (0.71) TDP1HPGDKDM4EALDH1A1MEN1
SCHEMBL27338889 0.86 MAPT (0.62) TDP1HPGDKDM4EALDH1A1MEN1
SCHEMBL1149765 0.84 KDM4E (0.69) TDP1HPGDKDM4EALDH1A1MEN1
SCHEMBL9397292 0.83 KDM4E (0.68) TDP1HPGDKDM4EALDH1A1MEN1
SCHEMBL8124194 0.83 KDM4E (0.68) TDP1HPGDKDM4EALDH1A1MEN1
SCHEMBL5012113 0.83 KDM4E (0.68) TDP1HPGDKDM4EALDH1A1MEN1
SCHEMBL30716979 0.82 KDM4E (0.66) TDP1HPGDKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0575345-B1 NONAQUEOUS POLYMERIC REAGENT COMPOSITIONS AND APPLICATIONS THEREOF BOEHRINGER MANNHEIM CORP (US) 1999-03-03 EP claimed
EP-0420893-B1 REDUCIBLE INDICATORS CONTAINING PYROGALLOL AND USE THEREOF BOEHRINGER MANNHEIM CORP (US) 1995-07-26 EP claimed
US-3947377-A ENZYMATIC DETECTION OF GLUCOSE BOEHRINGER MANNHEIM GMBH (DT) 1976-03-30 US claimed
EP-0918881-B1 DRY REAGENT TEST STRIP COMPRISING BENZIDINE DYE PRECURSOR AND ANTIPYRINE COMPOUND AMIRA MEDICAL (US) 2004-02-11 EP disclosed
EP-0918881-A1 DRY REAGENT TEST STRIP COMPRISING BENZIDINE DYE PRECURSOR AND ANTIPYRINE COMPOUND Mercury Diagnostics Inc. (US) 1999-06-02 EP disclosed
US-5824491-A OXIDASE ENZYME AS ANALYTE ON SUBSTRATE, FORMING PEROXIDE, BENZIDINE DYE PRECURSOR, PEROXIDASE ENZYME WITH ANTIPYRENE COMPOUND MERCURY DIAGNOSTICS, INC. (US) 1998-10-20 US disclosed
WO-1997044482-A1 DRY REAGENT TEST STRIP COMPRISING BENZIDINE DYE PRECURSOR AND ANTIPYRINE COMPOUND MERCURY DIAGNOSTICS INC. (US) 1997-11-27 WO disclosed
EP-0420893-B1 REDUCIBLE INDICATORS CONTAINING PYROGALLOL AND USE THEREOF BOEHRINGER MANNHEIM CORP (US) 1995-07-26 EP disclosed
US-5084395-A A chromogen and a pyrogallol derivative as a detector BOEHRINGER MANNHEIM GMBH (DE) 1992-01-28 US disclosed
US-4971918-A KIT WITH A DETECTABLE COLOR SIGNAL FOR DETECTION OF BLOOD, UR INE ETC FOR DRUGS, GLUCOSE BOEHRINGER MANNHEIM CORPORATION (US) 1990-11-20 US disclosed
US-3988208-A FOR GLUCOSE BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-10-26 US disclosed
US-3975398-A INDICATOR FOR DETERMINATION OF GLUCOSE BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-08-17 US disclosed
US-3947377-A ENZYMATIC DETECTION OF GLUCOSE BOEHRINGER MANNHEIM GMBH (DT) 1976-03-30 US disclosed
US-3947377-A ENZYMATIC DETECTION OF GLUCOSE BOEHRINGER MANNHEIM GMBH (DT) 1976-03-30 US disclosed