SCHEMBL6550807

SCHEMBL6550807

Cc1cccc(C)c1Oc1c(C#N)c(C#N)c(F)c(Oc2c(Cl)cccc2Cl)c1Oc1c(Cl)cccc1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.37
AR P10275 3/20 0.36
HTR1A P08908 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC22A12 Q96S37 1/20 0.35
BCAT2 O15382 1/20 0.35
BCAT1 P54687 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 2/20 0.32
S1PR1 P21453 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6552104 0.84 AR (0.34) KDM4EARHTR1ASLC6A2SLC22A12
SCHEMBL6551650 0.81 AR (0.43) KDM4EARMEN1KMT2ACYP1A2
SCHEMBL7870097 0.81 AR (0.42) KDM4EARHTR1ASLC6A2SLC22A12
SCHEMBL7861699 0.81 KDM4E (0.36) KDM4EHTR1ASLC6A2HSP90AA1MEN1
SCHEMBL2456144 0.76 AR (0.39) ARSLC22A12BCAT2BCAT1HSP90AA1
SCHEMBL10826520 0.73 AR (0.41) KDM4EARHTR1ASLC6A2SLC22A12
SCHEMBL18339182 0.71 HSP90AA1 (0.41) KDM4EARHSP90AA1MEN1KMT2A
SCHEMBL27604058 0.71 AR (0.44) KDM4EARHTR1ASLC6A2SLC22A12
SCHEMBL27603939 0.70 AR (0.38) ARHTR1ASLC6A2SLC22A12BCAT2
SCHEMBL3888717 0.69 L3MBTL1 (0.36) ARCYP1A2CYP2C19L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1072959-B1 Phthalocyanine compound, method for production thereof, and near infrared absorption dye using the compound NIPPON CATALYTIC CHEM IND (JP) 2004-12-08 EP disclosed
US-6323340-B1 Phthalocyanine compound, method for production thereof, and near infrared absorption dye using the compound NIPPON SHOBUKAI CO., LTD. (JP) 2001-11-27 US disclosed
EP-1072959-A1 Phthalocyanine compound, method for production thereof, and near infrared absorption dye using the compound NIPPON SHOKUBAI KABUSHIKI KAISHA (JP) 2001-01-31 EP disclosed