SCHEMBL7870097

SCHEMBL7870097

Cc1cccc(C)c1Oc1c(F)c(F)c(C#N)c(C#N)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.42
CYP1A2 P05177 3/20 0.38
CYP2C19 P33261 3/20 0.38
TSHR P16473 1/20 0.34
HSP90AA1 P07900 2/20 0.34
CYP3A4 P08684 1/20 0.34
SLC22A12 Q96S37 1/20 0.33
BCAT2 O15382 1/20 0.33
BCAT1 P54687 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 4/20 0.32
MAPT P10636 4/20 0.32
KDM4E B2RXH2 3/20 0.32
POLB P06746 2/20 0.32
HPGD P15428 2/20 0.32
LMNA P02545 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SCN8A Q9UQD0 2/20 0.32
PKM P14618 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10826520 0.88 AR (0.41) ARCYP1A2CYP2C19TSHRHSP90AA1
SCHEMBL7861721 0.83 AR (0.43) ARCYP1A2CYP2C19TSHRCYP3A4
SCHEMBL3619566 0.81 TRPV4 (0.31)
SCHEMBL6550807 0.81 KDM4E (0.37) ARCYP1A2CYP2C19TSHRHSP90AA1
SCHEMBL7869301 0.80 TSHR (0.43) CYP1A2CYP2C19TSHRSMN1; SMN2ALDH1A1
SCHEMBL7870109 0.80 AR (0.45) ARTSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL7861699 0.79 KDM4E (0.36) CYP1A2CYP2C19HSP90AA1CYP3A4ALDH1A1
SCHEMBL13439997 0.79 TRPV4 (0.30)
SCHEMBL6551650 0.78 AR (0.43) ARCYP1A2CYP2C19CYP3A4SMN1; SMN2
SCHEMBL7866694 0.77 MEN1 (0.33) SMN1; SMN2ALDH1A1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882768-B1 Method for producing of phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2001-12-19 EP disclosed
US-6034236-A REACTING A PHTHALONITRILE WITH A METAL OXIDE IN PRESENCE OF A SULFONIC ACID CATALYST NIPPON SHOKUBAI CO., LTD. (JP) 2000-03-07 US disclosed
EP-0882768-A2 Method for producing of phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-09 EP disclosed