Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700006 | 0.89 | P2RX7 (0.46) | KDM4EHPGDTSHRHSD17B10MAPT | |
| Trifluoroacetic Acid SCHEMBL6551836 | 0.86 | HIF1A (0.43) | KDM4EHPGDTSHRHSD17B10MAPT | |
| SCHEMBL11567016 | 0.86 | MAPT (0.46) | KDM4EHPGDTSHRHSD17B10MAPT | |
| SCHEMBL25796826 | 0.83 | HPGD (0.50) | KDM4EHPGDTSHRHSD17B10MAPT | |
| SCHEMBL19921051 | 0.82 | CYP19A1 (0.40) | KDM4EHPGDTSHRHSD17B10MAPT | |
| SCHEMBL25796823 | 0.82 | ALDH1A1 (0.49) | KDM4EHPGDTSHRHSD17B10MAPT | |
| SCHEMBL28661673 | 0.82 | BACE1 (0.51) | KDM4EHSD17B10MAPTHIF1AALDH1A1 | |
| SCHEMBL20291630 | 0.80 | L3MBTL1 (0.47) | KDM4EHPGDTSHRHSD17B10MAPT | |
| SCHEMBL10055008 | 0.79 | MAPT (0.53) | KDM4EHPGDMAPTHIF1AALDH1A1 | |
| SCHEMBL11593195 | 0.79 | MAPT (0.61) | HPGDMAPTP2RX7CYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482929-A1 | USE OF SUBSTITUTED 3-PHENYL-5-ALKOXY-1,3,4-OXDIAZOLE-2-ONE FOR PRODUCING MEDICAMENTS THAT INHIBIT PANCREATIC LIPASE | Aventis Pharma Deutschland GmbH (DE) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003072098-A1 | USE OF SUBSTITUTED 3-PHENYL-5-ALKOXY-1,3,4-OXDIAZOLE-2-ONE FOR PRODUCING MEDICAMENTS THAT INHIBIT PANCREATIC LIPASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-09-04 | — | — | WO | disclosed |