SCHEMBL6550984

SCHEMBL6550984

O=C(Cl)c1cc(C(=O)Cl)oc(=O)c1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.36
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
MEN1 O00255 1/20 0.30
GLA P06280 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11853770 0.77 KDM4E (0.68) KMT2AKDM4EMAPTNPC1RAB9A
SCHEMBL1843937 0.71 KDM4E (0.61) KMT2AKDM4EMAPT
SCHEMBL13490121 0.70 KDM4E (0.44) KMT2AKDM4EMAPTNPC1RAB9A
SCHEMBL22345883 0.70 KDM4E (0.59) KMT2AKDM4EMAPT
SCHEMBL38576 0.69 ALDH1A1 (0.40)
SCHEMBL9357016 0.68 DAO (0.31) KMT2AMEN1
Hydrochloric Acid SCHEMBL18918955 0.67 ALDH1A1 (0.39)
SCHEMBL10667752 0.67 ALDH1A1 (0.38) KMT2AKDM4EMAPTNPC1RAB9A
Ethane SCHEMBL29138437 0.65 ALDH1A1 (0.37)
Benzene SCHEMBL28576976 0.65 TDP1 (0.43) MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1088844-B1 POLYAMIDE AND PROCESS FOR PRODUCING THE SAME COSMO RES INST (JP) 2004-12-15 EP disclosed
EP-1092741-B1 POLYESTER AND PROCESS FOR PRODUCING THE SAME COSMO RES INST (JP) 2003-09-10 EP disclosed
US-6340739-B1 POLYAMIDE USING DICARBOXYPYRANONE WITH DIAMINE COMPOUND COSMO RESEARCH INSTITUTE (JP) 2002-01-22 US disclosed
US-6303745-B1 FROM THE POLYCONDENSATION OF A 2H-PYRAN-2-ONE-4,6-DICARBOXYLIC ACID OR DERIVATIVE AND A GLYCOL COSMO RESEARCH INSTITUTE (JP) 2001-10-16 US disclosed
EP-1092741-A1 POLYESTER AND PROCESS FOR PRODUCING THE SAME Cosmo Research Institute (JP) 2001-04-18 EP disclosed
EP-1088844-A1 POLYAMIDE AND PROCESS FOR PRODUCING THE SAME Cosmo Research Institute (JP) 2001-04-04 EP disclosed