Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4561830 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7125613 | 0.81 | — | — | |
| SCHEMBL7154902 | 0.79 | KDM4E (0.31) | ALDH1A1LMNASMN1; SMN2KDM4ETHRB | |
| SCHEMBL2145053 | 0.79 | MGAM (0.33) | ALDH1A1LMNA | |
| SCHEMBL485763 | 0.78 | KMT2A (0.36) | ALDH1A1SMN1; SMN2THRBMAPK1 | |
| SCHEMBL3401546 | 0.78 | ACACB (0.32) | — | |
| SCHEMBL126477 | 0.78 | CAD (0.39) | HTT | |
| SCHEMBL8447042 | 0.77 | POLB (0.38) | SMN1; SMN2MAPK1 | |
| Methyl Alcohol SCHEMBL22551139 | 0.76 | CAD (0.38) | — | |
| SCHEMBL1042116 | 0.76 | SMN1; SMN2 (0.36) | ALDH1A1LMNASMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814108-B1 | Silyl-linked polyamidoamines and their preparation | HERCULES INC (US) | 2004-02-11 | — | — | EP | claimed |
| US-5990333-A | A THERMOSETTING POLYAMIDE OF A DICARBOXYLIC ACID AND A POLYAMINE, E.G. DIETHYLENETRIAMINE MODIFIED BY A HYDROLYZABLE REACTIVE SILANETRIOL; SIZING CELLULOSE, FIBERS AND PAPER SIZING; WET AND DRY STRENGTH OF PAPER PULP; CREPING ADHESIVE | HERCULES INCORPORATED (US) | 1999-11-23 | — | — | US | claimed |
| EP-0814108-A1 | Silyl-linked polyamidoamines and their preparation | HERCULES INCORPORATED (US) | 1997-12-29 | — | — | EP | claimed |
| EP-0814108-B1 | Silyl-linked polyamidoamines and their preparation | HERCULES INC (US) | 2004-02-11 | — | — | EP | disclosed |
| US-6315865-B1 | Silyl-linked polyamidoamine and their preparation | HERCULES INCORPORATED | 2001-11-13 | — | — | US | disclosed |
| US-5990333-A | A THERMOSETTING POLYAMIDE OF A DICARBOXYLIC ACID AND A POLYAMINE, E.G. DIETHYLENETRIAMINE MODIFIED BY A HYDROLYZABLE REACTIVE SILANETRIOL; SIZING CELLULOSE, FIBERS AND PAPER SIZING; WET AND DRY STRENGTH OF PAPER PULP; CREPING ADHESIVE | HERCULES INCORPORATED (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0814108-A1 | Silyl-linked polyamidoamines and their preparation | HERCULES INCORPORATED (US) | 1997-12-29 | — | — | EP | disclosed |
| EP-0541511-B1 | Siloxan-containing derivatives of polysaccharides and their use in making paper | NAT STARCH CHEM INVEST (US) | 1997-08-06 | — | — | EP | disclosed |
| EP-0385396-B1 | Organosiloxane-containing polysaccharides | NAT STARCH CHEM INVEST (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0541511-A2 | Siloxan-containing derivatives of polysaccharides and their use in making paper | National Starch and Chemical Investment Holding Corporation (US) | 1993-05-12 | — | — | EP | disclosed |
| EP-0540506-A2 | Organosiloxane-containing polysaccharides | National Starch and Chemical Investment Holding Corporation (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5004791-A | Glass fiber sizing composition | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |
| US-4973680-A | PAPERMAKING SIZES | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0385396-A1 | Organosiloxane-containing polysaccharides | National Starch and Chemical Investment Holding Corporation (US) | 1990-09-05 | — | — | EP | disclosed |