SCHEMBL3401546

SCHEMBL3401546

CCO[Si](OCC)(OCC)C(CC)NC(=O)OC

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACACB O00763 2/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP8 P22894 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1042116 0.87 SMN1; SMN2 (0.36)
SCHEMBL4561830 0.84 ALDH1A1 (0.32)
SCHEMBL1038146 0.84 MMP1 (0.32) ACACBCA12CA1CA2MMP1
SCHEMBL28570007 0.83 ACACB (0.31) ACACB
SCHEMBL2145053 0.82 MGAM (0.33)
SCHEMBL7154902 0.82 KDM4E (0.31) ACACB
SCHEMBL6517880 0.82 CTSK (0.43) CA1CA2
SCHEMBL126477 0.81 CAD (0.39)
Methyl Alcohol SCHEMBL22551139 0.79 CAD (0.38)
SCHEMBL17261296 0.79 CYP1A2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100324205-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2010-12-23 US disclosed
EP-2247669-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION Construction Research & Technology GmbH (DE) 2010-11-10 EP disclosed
WO-2009095325-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-08-06 WO disclosed
EP-2085442-A1 Compounds containing fluoride with improved surface characteristics Evonik Degussa GmbH (DE) 2009-08-05 EP disclosed