SCHEMBL6551878

SCHEMBL6551878

Cc1ccc(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(OCCCCCCOC(N)=O)cc3O)n2)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDIA6 Q15084 1/20 0.37
NPC1 O15118 1/20 0.37
PLK1 P53350 2/20 0.37
PTPN11 Q06124 2/20 0.37
PARP10 Q53GL7 2/20 0.36
MAOB P27338 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PRMT1 Q99873 3/20 0.35
F2 P00734 2/20 0.35
ST14 Q9Y5Y6 2/20 0.35
PLAU P00749 1/20 0.35
GAA P10253 1/20 0.35
PRMT5 O14744 1/20 0.35
SLC22A2 O15244 1/20 0.35
SLC22A1 O15245 1/20 0.35
TMPRSS2 O15393 1/20 0.35
PTP4A3 O75365 1/20 0.35
SLC22A3 O75751 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7124098 0.95 PLK1 (0.35) PDIA6NPC1PLK1PTPN11PARP10
SCHEMBL7117619 0.87 PLK1 (0.38) PLK1PTPN11MAOBHTTTDP1
SCHEMBL8385501 0.86 TSHR (0.40) PLK1PTPN11MAOBHTTTDP1
SCHEMBL8385683 0.86 POLB (0.52) PLK1PTPN11MAOBHTTTDP1
SCHEMBL30887123 0.86 TSHR (0.40) PLK1PTPN11MAOBHTTTDP1
SCHEMBL30887155 0.86 POLB (0.52) PLK1PTPN11MAOBHTTTDP1
SCHEMBL31103750 0.85 CNR2 (0.44) PLK1PTPN11
SCHEMBL6552608 0.85 PDK2 (0.39) NPC1PTPN11L3MBTL1GAA
SCHEMBL45412 0.85 NR5A1 (0.49) NPC1PLK1PTPN11L3MBTL1GAA
SCHEMBL22216823 0.85 NR5A1 (0.49) NPC1PLK1PTPN11L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6762250-B2 TRANSPARENCY, FLUIDITY; CONTAINING POLYSILOXANE HAVING AT LEAST AROMATIC HYDROCARBON FUNCTIONALITY, CARBOXYLIC ACID ESTER AND/OR ETHER LINKAGES AND PHOSPHORIC ESTER GROUP ATTACHMENT MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-07-13 US disclosed
US-20040054116-A1 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION 2004-03-18 US disclosed
EP-1034169-B1 TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS CIBA SC HOLDING AG (CH) 2004-02-11 EP disclosed
US-20030065066-A1 Triazine UV absorbers comprising amino resins JAKIELA DENNIS JOHN (US) 2003-04-03 US disclosed
US-6365652-B2 AMIDO OR CARBAMATE SUBSTITUTED TRISARYL-1,3,5-TRIAZINES USED AS ACTINIC RADIATION STABILIZER BY INCORPORATING THE ABOVE COMPOUND INTO THE ORGANIC POLYMER BY CHEMICAL BONDING CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-02 US disclosed
US-20010037022-A1 Trisaryl-1,3,5-triazine ultraviolet light absorbers GUPTA RAM BABOO (US) 2001-11-01 US disclosed
US-6265576-B1 STABILIZERS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-24 US disclosed
EP-1034169-A1 TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS Ciba SC Holding AG (CH) 2000-09-13 EP disclosed
WO-1999026935-A1 TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS CYTEC TECHNOLOGY CORP. (US) 1999-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037022-A1 Trisaryl-1,3,5-triazine ultraviolet light absorbers CRYZ, ERCC5, TELO2 PDIA6 4317/4885NPC1 2191/4885PLK1 4497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.