Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27470965 | 1.00 | MGLL (0.54) | MGLLRAB9ANPC1CASP1MAPT | |
| SCHEMBL6251009 | 0.86 | TP53 (0.59) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL5089732 | 0.84 | MGLL (0.56) | MGLLRAB9ANPC1CASP1MAPT | |
| SCHEMBL11045142 | 0.84 | STS (0.44) | KMT2ATP53TSHRPLA2G4BSTS | |
| SCHEMBL10295292 | 0.84 | MGLL (0.56) | MGLLRAB9ANPC1CASP1MAPT | |
| SCHEMBL27585783 | 0.83 | MGLL (0.58) | MGLLRAB9ANPC1CASP1MAPT | |
| SCHEMBL7814101 | 0.82 | CTRC (0.54) | MGLLRAB9ANPC1CASP1MAPT | |
| SCHEMBL19922885 | 0.80 | MGLL (0.50) | MGLLRAB9ANPC1CASP1MAPT | |
| SCHEMBL28261584 | 0.80 | MGLL (0.50) | MGLLRAB9ANPC1CASP1MAPT | |
| SCHEMBL1765589 | 0.80 | MGLL (0.48) | MGLLRAB9ANPC1CASP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755385-B1 | CHELANT COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2004-02-11 | — | — | EP | disclosed |
| US-5798089-A | Chelant moieties linked to an aryl moiety by an interrupted alkylene linker | NYCOMED SALUTAR, INC. (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0755385-A1 | CHELANT COMPOUNDS | NYCOMED IMAGING AS (NO) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028392-A1 | CHELANT COMPOUNDS | NYCOMED SALUTAR INC. (US) | 1995-10-26 | — | — | WO | disclosed |