Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552914 | 0.78 | KCNN4 (0.40) | MEN1KMT2AMAPK1LMNAGRIN2D | |
| SCHEMBL14149500 | 0.70 | CYP19A1 (0.70) | MEN1KMT2ANPSR1CYP19A1HTT | |
| SCHEMBL12157084 | 0.70 | CYP19A1 (0.48) | MEN1KMT2ANPSR1CYP19A1HTT | |
| SCHEMBL4352232 | 0.69 | MEN1 (0.52) | MEN1KMT2ANPSR1CYP19A1TSHR | |
| SCHEMBL4787209 | 0.69 | MEN1 (0.52) | MEN1KMT2ANPSR1CYP19A1TSHR | |
| SCHEMBL6280416 | 0.69 | KMT2A (0.52) | MEN1KMT2ANPSR1CYP19A1TSHR | |
| SCHEMBL14395067 | 0.69 | CYP19A1 (0.47) | MEN1KMT2ANPSR1CYP19A1TSHR | |
| SCHEMBL13930871 | 0.69 | MEN1 (0.52) | MEN1KMT2ANPSR1CYP19A1TSHR | |
| SCHEMBL6552393 | 0.68 | SMN1; SMN2 (0.41) | MEN1KMT2ANPSR1CYP19A1POLB | |
| SCHEMBL13749516 | 0.67 | CYP19A1 (0.46) | MEN1KMT2ANPSR1CYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485106-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-15 | — | — | EP | claimed |
| WO-2003070179-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | claimed |
| EP-1485106-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003070179-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | disclosed |